16
Participants
Start Date
January 7, 2021
Primary Completion Date
April 12, 2021
Study Completion Date
April 12, 2021
[14C]-GDC-9545
Participants will receive a single oral dose of \[14C\]-GDC-9545 capsule, 30 milligrams (mg) (not more than \[NMT\] 4.6 megabecquerel \[MBq\]; 124 microcurie \[μCi\]) with approximately 240 millilitres (mL) water in the fasted state.
GDC-9545 Solution for Infusion
Treatment B: 30 mg GDC-9545 as a solution for infusion, 3 mg/mL administered intravenously (IV) in 10 mL as an infusion over 30 minutes.
GDC-9545/F12 Capsule
Treatment C: GDC-9545/F12 capsule, 30 mg, administered orally with approximately 240 mL water.
GDC-9545/F18 Capsule
Treatment D: GDC-9545/F18 capsule, 30 mg, administered orally with approximately 240 mL water.
Quotient Sciences, Nottingham
Lead Sponsor
Genentech, Inc.
INDUSTRY