APG-2575 Monotherapy or in Combination With Lenalidomide/DXMS in Subjects With Relapsed or Refractory Multiple Myeloma

PHASE1/PHASE2UnknownINTERVENTIONAL
Enrollment

48

Participants

Timeline

Start Date

April 13, 2021

Primary Completion Date

January 31, 2024

Study Completion Date

May 31, 2024

Conditions
Multiple Myeloma
Interventions
DRUG

APG-2575

APG-2575 orally once daily, every 28 days as a cycle.

DRUG

Rd

Lenalidomide administered at a dose of 25 mg orally (PO) on Days 1 through 21 of each 28-day cycle, dexamethasone administered at a dose of 40 mg (or 20 mg for patients\>75 years old) on Days 1, 8, 15, and 22 of a repeated 28-day cycle.

Trial Locations (12)

100020

NOT_YET_RECRUITING

Beijing Chao-yang Hospital of Capital Medical University, Beijing

210029

NOT_YET_RECRUITING

People's hospital of Jiangsu Province, Nanjing

215006

RECRUITING

The First Affiliated Hospital of Soochow University, Suzhou

215316

NOT_YET_RECRUITING

Union Hospital Tongji Medical College of Huazhong University of Science ang Technology, Wuhan

310003

NOT_YET_RECRUITING

The First Affilated Hospital of Zhejiang University School of Medicine, Hangzhou

NOT_YET_RECRUITING

The Second Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou

430062

NOT_YET_RECRUITING

Zhongnan Hospital of Wuhan University, Wuhan

450003

NOT_YET_RECRUITING

Henan Cancer Hospital, Zhengzhou

510060

NOT_YET_RECRUITING

Sun Yat-sen University Cancer Center, Guangzhou

510080

NOT_YET_RECRUITING

Guangdong Province People's Hospital, Guangzhou

NOT_YET_RECRUITING

The First Affiliated Hospital of Sun Yat-sen University, Guangzhou

518025

NOT_YET_RECRUITING

Shenzhen Second People's Hospital, Shenzhen

Sponsors
All Listed Sponsors
lead

Ascentage Pharma Group Inc.

INDUSTRY