Nasal Poly-ICLC (Hiltonol®) in Healthy COVID-19 Vaccinated Adults

PHASE1CompletedINTERVENTIONAL
Enrollment

43

Participants

Timeline

Start Date

July 21, 2021

Primary Completion Date

April 1, 2023

Study Completion Date

April 1, 2023

Conditions
COVID - 19
Interventions
DRUG

Poly-ICLC (Hiltonol®) or Placebo

The safety cohort (Cohort A) consists of 13 patients who will be randomized to receive 2 cycles of the study drug (N10) or 2 placebo cycles (N3).

DRUG

Poly-ICLC (Hiltonol®) or Placebo

The expansion cohort will receive 3 cycles of therapy. A total of 30 patients will be accrued and randomized 4:1 to receive drug (N=24) or placebo (N=6).

Trial Locations (1)

T2N 4Z6

Health Research Innovation Centre, Calgary

Sponsors

Lead Sponsor

All Listed Sponsors
collaborator

University of Calgary

OTHER

lead

Oncovir, Inc.

INDUSTRY