Lorazepam Effects on Neuroimaging Measures

EARLY_PHASE1WithdrawnINTERVENTIONAL
0
Timeline

Start Date

January 31, 2022

Primary Completion Date

December 31, 2022

Study Completion Date

December 31, 2022

Conditions
LorazepamNeuroimaging
Interventions
DRUG

Lorazepam 1Mg Tablet

"1 mg, white, five-sided (shield shape) tablet with a raised A on one side and BPI and 64 impressed on scored reverse side. NDC 0187-0064-01 - Bottles of 100 tablets; NDC 0187-0064-50 - Bottles of 500 tablets; NDC 0187-0064-10 - Bottles of 1000 tablets.~The pharmacy at the Zucker Hillside Hospital will encapsulate both lorazepam 1 mg and placebo pills to make them look the same. On the day of the scan, the research coordinator or the PI will pick up the blinded study medication (lorazepam or placebo) and will administer it to the participant. One hour later, the participant will be placed in the scanner to complete the MRI."

DRUG

Placebo

Placebo will be purchased and encapsulated by the pharmacy at the Zucker Hillside Hospital.

Trial Locations (1)

11004

The Zucker Hillside Hospital, Glen Oaks

Sponsors

Lead Sponsor

All Listed Sponsors
lead

Northwell Health

OTHER