CPX-351 as a Novel Approach for the Treatment of Older Patients With AML and MDS

PHASE2Active, not recruitingINTERVENTIONAL
Enrollment

13

Participants

Timeline

Start Date

January 14, 2021

Primary Completion Date

October 10, 2025

Study Completion Date

October 10, 2026

Conditions
Refractory Acute Myeloid LeukemiaRelapsed Acute Myelomonocytic LeukemiaMyelodysplastic Syndromes
Interventions
DRUG

CPX-351

"Induction phase: CPX-351 15 mg/m\^2 on days 1 and 3 of each 28-day cycle for up to a total of 6 cycles in the absence of unacceptable toxicity~Maintenance phase: CPX-351 7.5 mg/m\^2 on days 1 and 3 for two cycles alternating with 15 mg/m\^2 for one cycle. Participants may receive up to 12 cycles of maintenance phase in the absence of unacceptable toxicity."

Trial Locations (1)

44106-5065

Cleveland Clinic, Case Comprehensive Cancer Center, Cleveland

All Listed Sponsors
lead

Case Comprehensive Cancer Center

OTHER