Clinical Investigation Study to Evaluate the Consistency and Reproducibility of Two Consecutive Mosquito Feeding Assays

CompletedOBSERVATIONAL
Enrollment

42

Participants

Timeline

Start Date

March 9, 2021

Primary Completion Date

December 20, 2021

Study Completion Date

December 20, 2021

Conditions
Malaria
Interventions
OTHER

Direct Skin Feeding Assay (DSFA)

In the direct feeding assay a cup with 60 unfed, sterile insectary-reared Anopheles gambiae mosquitoes will be allowed to feed on a participant's calf or arm for 15 minutes.

DRUG

Primaquine

Participants will receive one dose of primaquine 26.3 mg tablet on Day 2 after completion of the direct feeding assay.

DRUG

Artemether/Lumefantrine

Participants will receive artemether (80 mg) and lumefantrine (480 mg) combination tablets twice a day for 3 days, starting after completion of the direct feeding assay on Day 2.

Trial Locations (1)

Unknown

KEMRI, Kombewa

Sponsors
All Listed Sponsors
collaborator

Walter Reed Army Institute of Research (WRAIR)

FED

collaborator

Kenya Medical Research Institute

OTHER

lead

PATH

OTHER