Biomarker-guided Intervention to Prevent Acute Kidney Injury

NACompletedINTERVENTIONAL
Enrollment

1,180

Participants

Timeline

Start Date

November 17, 2020

Primary Completion Date

June 24, 2024

Study Completion Date

September 9, 2024

Conditions
Acute Kidney Injury
Interventions
OTHER

"Comprehensive Implementation of the Bundle recommended by the Kidney Disease: Improving Global Outcomes Group (KDIGO bundle)"

"Implementation of the KDIGO bundle for at least 12 hours~1. discontinuation of all nephrotoxic drugs when possible~2. optimization of volume status and hemodynamic parameters (consideration of a functional hemodynamic monitoring)~3. close monitoring of serum creatinine, fluid balance and urinary output~4. avoidance of hyperglycemia~5. considerations of alternatives to radiocontrast agents~6. discontinuation of angiotensin converting enzyme inhibitors and angiotensin receptor blockers in the perioperative period~7. avoidance of HES, gelatin, and chlorid-rich solutions"

Trial Locations (37)

Unknown

Centre Hospitalier Universitaire de Clermont-Ferrand, Clermont-Ferrand

Service d´Anesthésie-Réanimation, Hôpital Edouard Herriot, Hospices Civils de Lyon, Lyon

Centre Hospitalier Universitaire de Reims, Reims

Department of Anaesthesiology and Intensive Care Medicine, Klinikum Bayreuth GmbH, Bayreuth

Department of Anesthesiology, Intensive Care Medicine and Pain Therapy, University Hospital Knappschaftskrankenhaus, Ruhr University Bochum, Bochum

Department of Anesthesiology and Intensive Care Medicine, University Hospital Bonn, Bonn

Department of Anesthesiology, Intensive Care and Pain Medicine, Klinikum Dortmund, Dortmund

"Department of Anesthesiology and Intensive Care Medicine, University Hospital Carl Gustav Carus, Technische Universität Dresden", Dresden

Department of Anesthesiology, University Hospital Düsseldorf, Heinrich-Heine-University Duesseldorf, Düsseldorf

Department of Anesthesiology and Intensive Care Medicine, University Hospital Essen, University Duisburg-Essen, Essen

Department of Anesthesiology, University Medical Center, Georg-August-University, Göttingen

Department of Anesthesiology, Heidelberg University Hospital, Heidelberg

Department of Anesthesiology and Intensive Care Medicine, Philipps-University, Marburg

Department of Anaesthesiology, Intensive Care and Pain Medicine, University Hospital, Münster

Department of Anesthesiology, Department of Anesthesiology and Critical Care, Franziskus Hospital Münster, Münster

Department of Anesthesiology and Intensive Care Medicine, University Hospital Tübingen, Eberhard Karls University Tübingen, Tübingen

IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna

Department of Translational Medicine and for Romagna, St. Anne's Archbishop Hospital, University of Ferrara, Ferrara

Department of Health Sciences, Section of Anesthesiology, Intensive Care and Pain Medicine, University of Florence; Department of Anesthesia and Intensive Care, Section of Oncological Anesthesia and Intensive care, Azienda Ospedaliero Careggi, Florence

Santa Chiara Regional Hospital, APSS Trento, Trento

Department of Anesthesiology and Intensive Care, San Bortolo Hospital, Vicenza

Department of Anaesthesiology, Laboratory of Experimental Intensive Care and Anaesthesiology (L.E.I.C.A.), Amsterdam UMC, Location Academic Medical Centre (AMC), Amsterdam, University of Amsterdam, Amsterdam

Department of Anaesthesiology and Intensive Care Medicine, Parc de Salut Mar, Barcelona

Hospital de Igualada, Barcelona

Department of Anesthesia and Perioperative Care, Infanta Leonor University Hospital, Madrid

Department of Anesthesiology, Hospital Universitario Ramón y Cajal, Madrid

Hospital 12 de Octubre, Madrid

Hospital Clínico San Carlos de Madrid, Madrid

Servicio de Anestesiologia y Reanimación, Hosp. Universitario de La Princesa, Madrid

Department of Anaesthesiology and Surgical Critical Care, Hospital Universitario Marqués de Valdecilla, Santander

Hospital Universitario Virgen Macarena, Seville

Adult Intensive Care Unit, Centre Hospitalier Universitaire Vaudois (CHUV), Lausanne

Centre for Experimental Medicine, School of Medicine, Dentistry, and Biomedical Sciences, Queen's University Belfast, Belfast

Intensive Care Unit, Royal Surrey County Hospital, Guildford

Department of Anaesthetics and Critical Care, Harefield Hospital, Harefield

Intensive Care Unit, Royal Liverpool University Hospital, Liverpool

Department of Critical Care, King's College London, Guy's & St Thomas' Hospital, London

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

BioMérieux

INDUSTRY

lead

University Hospital Muenster

OTHER