A Study of AK104 in Patients With Locally Advanced or Metastatic Non-small Cell Lung Cancer

PHASE1/PHASE2CompletedINTERVENTIONAL
Enrollment

46

Participants

Timeline

Start Date

November 24, 2020

Primary Completion Date

December 31, 2023

Study Completion Date

December 31, 2023

Conditions
Lung Cancer Non-Small Cell Stage IIIB/IIIC/IV
Interventions
DRUG

AK104 plus Carboplatin and Pemetrexed

Subjects receive AK104 15mg/kg intravenously (IV) plus pemetrexed 500 mg/m\^2 IV and carboplatin area under the curve (AUC) 5 IV on Day 1 of every 3-week cycle (Q3W) for 4 cycles followed by AK104 15mg/kg IV plus pemetrexed 500 mg/m\^2 IV Q3W until progression.

DRUG

AK104 plus Carboplatin and paclitaxel

Subjects receive AK104 15mg/kg intravenously (IV) plus paclitaxel 175 mg/m\^2 IV and carboplatin area under the curve (AUC) 5 IV on Day 1 of every 3-week cycle (Q3W) for 4 cycles followed by AK104 15mg/kg IV IV Q3W until progression.

Trial Locations (1)

Unknown

Sun Yat-Sen University Cancer Center, Guanzhou

Sponsors

Lead Sponsor

All Listed Sponsors
lead

Akeso

INDUSTRY

NCT04647344 - A Study of AK104 in Patients With Locally Advanced or Metastatic Non-small Cell Lung Cancer | Biotech Hunter | Biotech Hunter