46
Participants
Start Date
November 24, 2020
Primary Completion Date
December 31, 2023
Study Completion Date
December 31, 2023
AK104 plus Carboplatin and Pemetrexed
Subjects receive AK104 15mg/kg intravenously (IV) plus pemetrexed 500 mg/m\^2 IV and carboplatin area under the curve (AUC) 5 IV on Day 1 of every 3-week cycle (Q3W) for 4 cycles followed by AK104 15mg/kg IV plus pemetrexed 500 mg/m\^2 IV Q3W until progression.
AK104 plus Carboplatin and paclitaxel
Subjects receive AK104 15mg/kg intravenously (IV) plus paclitaxel 175 mg/m\^2 IV and carboplatin area under the curve (AUC) 5 IV on Day 1 of every 3-week cycle (Q3W) for 4 cycles followed by AK104 15mg/kg IV IV Q3W until progression.
Sun Yat-Sen University Cancer Center, Guanzhou
Lead Sponsor
Akeso
INDUSTRY