142
Participants
Start Date
May 2, 2024
Primary Completion Date
December 31, 2025
Study Completion Date
March 31, 2026
anti-hypertensive, home blood pressure measurement, telemonitoring and medication titration
"A medication algorithm based on the SPRINT trial protocol will be provided for patients in the home blood pressure measurement arm. The final choice and dose of antihypertensive treatment(s) will be at the discretion of the treating clinicians. If no contra-indications, indapamide or other thiazide diuretic and/or angiotensin-converting enzyme (ACE) inhibitor (perindopril or other) will be encouraged as initial therapy, with long-acting calcium-channel antagonists (eg.amlodipine) encouraged as third-line therapy.~Patients will have their home blood pressure monitoring diary reviewed by the study team. If SBP is out of the allocated target range, a prescription to titrate antihypertensive medication will be sent to the patient at least monthly."
Standard of Care Blood Pressure Management with Antihypertensives
Participants in the standard of care arm will receive antihypertensive therapy at the physician's discretion to the same treatment target of SBP \<130mmHg.
RECRUITING
Mater Misericordiae University Hospital, Dublin
St Vincent's University Hospital, Ireland
OTHER
Cork University Hospital
OTHER
Tallaght University Hospital
OTHER
HRB Stroke Trials Network Ireland
UNKNOWN
National University of Ireland, Galway, Ireland
OTHER
Mater Misericordiae University Hospital
OTHER
St. James's Hospital, Ireland
OTHER
Connolly Hospital Blanchardstown
OTHER
University College Dublin
OTHER