Preventing the Recurrence of Acute Pancreatitis by Alcohol and Smoking Cessation

NARecruitingINTERVENTIONAL
Enrollment

364

Participants

Timeline

Start Date

March 1, 2022

Primary Completion Date

December 31, 2027

Study Completion Date

June 30, 2028

Conditions
Acute PancreatitisRecurrent Acute Pancreatitis
Interventions
BEHAVIORAL

Standard intervention only

Standard intervention (SI) will be a part of standard care in all participating centers, and will be provided for all acute pancreatitis patients, who are hospitalized and their condition is alcohol induced. A specially trained study nurse will deliver the intervention, since they were found to be the most effective regarding the decrease in alcohol consumption and smoking. The cost- effectiveness of the intervention and the feasibility were also taken into account. The Assist-linked brief intervention according to the World Health Organization (WHO) will serve as the base for the intervention, with an avarage of 30 minutes, based on a review containing 69 randomized controlled trials, which concluded that longer intervention do not have additional benefit. The patients will be also educated about the disease course of acute pancreatitis during the standard intervention.

BEHAVIORAL

Standard intervention plus repeated intervention

Standard intervention (SI) will be performed as described above. The repeated intervention will be delivered by the former mentioned same nurse and will be structured similarly to the standard intervention. Every visit and intervention will be individually altered according to the motivation of the patient, but they will follow the same structure. The sessions can be divided into three main parts: first, highlighting the harmful effects of smoking and alcohol on the pancreatic functions. Secondly, a discussion about the motivation of the patient will happen. The last portion of the session will focus on the responsibility of the individual to reach the desired goal will be highlighted. To enhance the efficacy of our intervention we wish to provide feed-back for the patient based on laboratory testing: the mean corpuscular volume (MCV) and gamma glutamyl-transferase (GGT) values will be measured right before the interview. The study nurse will not take part in patient care.

Trial Locations (1)

7624

RECRUITING

Institute for Translational Medicine, University of Pécs, Pécs

All Listed Sponsors
lead

University of Pecs

OTHER