Mechanism of Response to IMFINZI Neoadjuvant Therapy in Non-small Cell Lung Cancer Patients Based on Multiple-omics Models

PHASE1/PHASE2UnknownINTERVENTIONAL
Enrollment

20

Participants

Timeline

Start Date

May 1, 2021

Primary Completion Date

May 1, 2024

Study Completion Date

March 31, 2025

Conditions
Non-small Cell Lung Cancer
Interventions
DRUG

Durvalumab

Durvalumab 1000 mg IV Q3W for 2 cycle + Followed by adjuvant treatment for 1 year with Durvalumab 1000 mg IV Q3W for 4 months and Durvalumab 1500mg Q4W for 8 months

DRUG

Albumin Paclitaxel

Albumin Paclitaxel 200-260 mg, depending on the patient's physical condition, for 2 cycle

DRUG

Carboplatin/Cisplatin

Carboplatin AUC 6 IV Q3W or Cisplatin 80mg/㎡ for 2 cycle

Trial Locations (1)

100000

RECRUITING

Peking Union Medical College Hospital, Beijing

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

AstraZeneca

INDUSTRY

lead

Peking Union Medical College Hospital

OTHER