Start Date
October 31, 2022
Primary Completion Date
December 31, 2023
Study Completion Date
December 31, 2023
Duloxetine
Three doses of 60 mg of oral duloxetine will be given to participants (right before operation, postop day 1, postop day 2)
Placebo
Three doses of placebo will be given to participants (right before operation, postop day 1, postop day 2).
Standard of care (SOC) for tibial plateau surgery
Postoperative IV administration of opioids via a patient controlled analgesia (PCA) system which utilizes a hydromorphone pump.
Westchester Medical Center, Valhalla
Boston Medical Center, Boston
Lead Sponsor
Boston Medical Center
OTHER