44
Participants
Start Date
August 28, 2022
Primary Completion Date
August 27, 2025
Study Completion Date
December 27, 2025
Pembrolizumab
Neoadjuvant pembrolizumab 200 mg IV every 3 weeks, given on cycle day 1. Adjuvant pembrolizumab 400 mg IV every 6 weeks, given on cycle day 1.
Carboplatin
Carboplatin AUC 6 IV (maximum dose: 900 mg) for squamous cell carcinoma, and AUC 5 IV (maximum dose: 750 mg) for non-squamous cell carcinoma, every 3 weeks, given on cycle day 1.
Paclitaxel
Paclitaxel 200 mg/m2 IV every 3 weeks, given on cycle day 1. Only given to participants with squamous cell carcinoma.
Pemetrexed
Pemetrexed 500 mg/m2 every 3 weeks, given on cycle day 1. Only given to participants with non-squamous cell carcinoma.
RECRUITING
McGill University Health Center, Montreal
McGill University Health Centre/Research Institute of the McGill University Health Centre
OTHER