Timing of FFR-guided PCI for Non-IRA in STEMI and MVD (OPTION-STEMI)

NAActive, not recruitingINTERVENTIONAL
Enrollment

994

Participants

Timeline

Start Date

December 30, 2019

Primary Completion Date

January 15, 2025

Study Completion Date

December 31, 2029

Conditions
Myocardial Infarction, AcuteMulti-Vessel Coronary Artery Stenosis
Interventions
PROCEDURE

Staged in-hospital or Immediate complete revascularization

Patients with ST-segment elevation myocardial infarction and multivessel disease will be randomized after primary PCI for IRA. All patients will be randomized to immediate complete revascularization group or staged revascularization group by 1:1 fashion. Non-IRA lesion which have equal or more than 70% diameter stenosis by visual estimation will be revascularized without FFR evaluation. Non-IRA lesion with diameter stenosis 50-70% by visual estimation will be evaluated using FFR device. In case of FFR value more than 0.8, non-IRA lesion wll be deferred without PCI. If FFR value was equal or less than 0.8, non-IRA lesion will be revascularized.

Trial Locations (14)

Unknown

The Catholic University of Korea, Bucheon St. Mary's Hospital, Bucheon-si

Gyeongsang National University Changwon Hospital, Changwon

Yeongnam University Medical Center, Daegu

GangNeung Asan Hospital, Gangneung

Chonnam National University Hospital, Gwangju

Chonbuk National University Hospital, Jeonju

Presbyterian Medical Center, Jeonju

Gyeongsang National University Hospital, Jinju

Koera University Guro Hospital, Seoul

Kyung Hee University Hospital, Seoul

The Catholic University of Korea, Seoul St. Mary's Hospital, Seoul

St. Carollo General Hospital, Suncheon

The Catholic University of Korea, Uijeongbu St. Mary's Hospital, Uijeongbu-si

Yonsei University, Wonju Severance Christian Hospital, Wŏnju

All Listed Sponsors
lead

Chonnam National University Hospital

OTHER

NCT04626882 - Timing of FFR-guided PCI for Non-IRA in STEMI and MVD (OPTION-STEMI) | Biotech Hunter | Biotech Hunter