A Proof of Concept Study of Pradigastat in Patients With Functional Constipation

PHASE2CompletedINTERVENTIONAL
Enrollment

181

Participants

Timeline

Start Date

September 22, 2020

Primary Completion Date

April 30, 2022

Study Completion Date

June 3, 2022

Conditions
Functional Constipation
Interventions
DRUG

Pradigastat Tablets 20mg

20mg, once daily, oral administration

DRUG

Pradigastat Tablets 40mg

40mg, once daily, oral administration

DRUG

Pradigastat Tablets 20mg matching Placebo

once daily, oral administration

DRUG

Pradigastat Tablets 40mg matching Placebo

once daily, oral administration

Trial Locations (25)

29464

PMG Research of Charleston, Mt. Pleasant

60201

Evanston Premier Healthcare Research, Evanston

Long Island Gastrointestinal Research Group LLP, New York

89106

Jubilee Clinical Research, Las Vegas

99202

Advanced Clinical Research-Meridian, Meridian

100000

Beijing Friendship Hospital, Capital Medical University, Beijing

136000

Siping Central People's Hospital, Siping

200000

Huashan Hospital Affiliated to Fudan University, Shanghai

Shanghai East Hospital, Shanghai

210000

Nanjing First Hospital, Nanjing

213002

Ruijin Hopsital, Shanghai

215000

Affiliated Hospital of Jiangsu University, Suzhou

223000

Huai'an First People's Hospital, Huai'an

225000

Yangzhou First People's Hospital, Yangzhou

310000

Sir Run Run Shaw Hospital Affiliated to Medical College of Zhejiang University, Hangzhou

The Second Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou

313000

Huzhou Central Hospital, Huzhou

325000

The First Affiliated Hospital of Wenzhou Medical University, Wenzhou

337000

Pingxiang People's Hospital, Pingxiang

362000

Quanzhou First Hospital, Quanzhou

410000

The Third Xiangya Hospital of Central South University, Changsha

430000

Renmin Hospital of Wuhan University, Wuhan

450000

People's Hospital of Zhengzhou, Zhengzhou

510000

Southern Medical University Nanfang Hospital, Guangzhou

050000

The Second Hospital of Hebei Medical University, Shijiazhuang

Sponsors

Lead Sponsor

Collaborators (1)

All Listed Sponsors
collaborator

Covance

INDUSTRY

lead

Anji Pharma

INDUSTRY