Clinical Evaluation of Safety and Tolerability of KDR2-2 Eye Drops in Healthy Volunteers With Pharmacokinetic Assessment

PHASE1UnknownINTERVENTIONAL
Enrollment

62

Participants

Timeline

Start Date

August 26, 2020

Primary Completion Date

March 31, 2021

Study Completion Date

June 30, 2021

Conditions
Corneal Neovascularization
Interventions
DRUG

KDR2-2

"KDR2-2 is a synthetic anti-angiogenic chemical compound with highly effective inhibition on vascular endothelial growth factor receptor-2 (VEGFR2), and an additional, moderate inhibitory effect on platelet-derived growth factor receptor β (PDGFRβ).~KDR2-2 suspension eye drop is in development for the treatment of corneal neovascularization."

DRUG

Placebo

Placebo : the formulation and the product process of placebo are the same as the KDR2-2 eye drops, but without API .

Trial Locations (1)

91206

RECRUITING

Parexel International, Glendale

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

Parexel

INDUSTRY

lead

Guangzhou HuiBoRui Biological Pharmaceutical Technology Co. Ltd

INDUSTRY