FaCT Trial (Facilitated Cascade Testing Trial)

NARecruitingINTERVENTIONAL
Enrollment

820

Participants

Timeline

Start Date

July 21, 2021

Primary Completion Date

March 31, 2026

Study Completion Date

December 31, 2026

Conditions
BRCA1 MutationBRCA2 Mutation
Interventions
OTHER

Family Letter (Standard of Care)

The family letter is given to probands in the standard of care arm and provides information on the familial mutation and serves to encourage first degree relatives to complete genetic testing.

OTHER

Educational Video

The educational video is provided by the clinical genetic testing laboratory and explains the importance and implications of genetic testing. This educational video is shared with first degree relatives in the intervention arm

OTHER

Mailed Saliva Kit for Genetic Testing

The FDR's email will be sent to the genetic testing lab, Invitae, which will allow them to log on to the online portal, create a unique account, and order a genetic testing saliva kit free of charge. The FDR will receive the kit and instructions in the mail. The FDR will collect the saliva sample and send the sample back to the genetic testing laboratory.

OTHER

Telephone Counseling

The FDR's will be contacted and receive post genetic testing phone counseling

Trial Locations (3)

10065

RECRUITING

Weill Cornell Medicine, New York

27710

RECRUITING

Duke University, Durham

77030

RECRUITING

MD Anderson Cancer Center, Houston

All Listed Sponsors
collaborator

Basser Research Center for BRCA

UNKNOWN

lead

Weill Medical College of Cornell University

OTHER