Study of CG0070 Combined With Nivolumab in Cisplatin Ineligible Patients With MIBC

PHASE1Active, not recruitingINTERVENTIONAL
Enrollment

21

Participants

Timeline

Start Date

October 26, 2020

Primary Completion Date

January 18, 2025

Study Completion Date

January 31, 2026

Conditions
Muscle-Invasive Bladder CarcinomaBladder Cancer
Interventions
DRUG

CG0070

CG0070 will be administered at a dose of 1x10\^12 vp intravesically following a sequence of bladder washes with 5% DDM and normal saline.

DRUG

Nivolumab

Two neoadjuvant doses of nivolumab 480 mg Q4W (every 4 weeks) for 2 doses (week 2 and 6)

Trial Locations (1)

33612

Moffitt Cancer Center, Tampa

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

CG Oncology, Inc.

INDUSTRY

collaborator

Richard M. Shulze Family Foundation

UNKNOWN

lead

H. Lee Moffitt Cancer Center and Research Institute

OTHER

NCT04610671 - Study of CG0070 Combined With Nivolumab in Cisplatin Ineligible Patients With MIBC | Biotech Hunter | Biotech Hunter