Measuring Fluid Flow in the Brain Using Alcohol and MRI in Healthy Participants

Diagnostic test is a single voxel MRS scan

Diagnostic test is a multi-voxel MRS imaging scan

Diagnostic test is a set of magnetic transfer weighted images

Participants will ingest an ethanol-containing beverage of approximately 0.5g/kg of ethanol mixed in 355 mL of a non-caffeinated, sugar-free carbonated drink which must be consumed in 5 minutes

Participants will breathe through the ClearMate, an MR-compatible non-rebreathing circuit which provides oxygen and carbon dioxide that quickly decreases a person's blood alcohol level.

Participants will have a peripheral arterial and peripheral venous line inserted and periodic arterial and venous blood samples will be measured for blood alcohol content.