Drug to Drug Interaction Study of KBP-5074 in Healthy Subjects

PHASE1CompletedINTERVENTIONAL
Enrollment

24

Participants

Timeline

Start Date

October 24, 2020

Primary Completion Date

November 30, 2020

Study Completion Date

November 30, 2020

Conditions
HealthyDrug Drug Interaction
Interventions
DRUG

Itraconazole

200 mg itraconazole, given orally as 20 mL × 10-mg/mL solution BID on Day 15, followed by QD dosing on Days 16 through 23, inclusive.

DRUG

Rifampin

600 mg rifampin, given orally as 2 × 300-mg capsules QD on Days 15 through 25, inclusive.

DRUG

KBP-5074

0.5 mg KBP-5074, given orally as 1 × 0.5-mg tablet on Days 1 and 19 or Days 1 and 21

Trial Locations (1)

65802

QPS Missouri, Springfield

Sponsors

Lead Sponsor

Collaborators (1)

All Listed Sponsors
collaborator

Covance

INDUSTRY

lead

KBP Biosciences

INDUSTRY