The KHENEREXT Study

PHASE2CompletedINTERVENTIONAL
Enrollment

11

Participants

Timeline

Start Date

August 9, 2021

Primary Completion Date

June 1, 2023

Study Completion Date

June 1, 2023

Conditions
Mitochondrial DiseasesMitochondrial DNA tRNALeu(UUR) m.3243A<G MutationMaternally Inherited Diabetes and Deafness (MIDD)Mitochondrial Encephalomyopathy, Lactic Acidosis and Stroke Like Episodes (MELAS)Chronic Progressive External Ophthalmoplegia (CPEO)
Interventions
DRUG

Oral administration of 100 mg KH176 twice daily

Drug: KH176

Trial Locations (4)

80336

Klinikum der Universität München Friedrich-Baur-Institut, München

DK2100

Rigshospitalet, University of Copenhagen, Copenhagen

Unknown

Radboud University Medical Center, Nijmegen

Institute for Ageing and Health Newcastle University, Newcastle upon Tyne

Sponsors
All Listed Sponsors
collaborator

Julius Clinical

INDUSTRY

collaborator

ProPharma Group

INDUSTRY

collaborator

Certara

INDUSTRY

lead

Khondrion BV

INDUSTRY

NCT04604548 - The KHENEREXT Study | Biotech Hunter | Biotech Hunter