Addition of Pembrolizumab to the Standard of Care Chemotherapy in Patient With SCCOHT

PHASE2RecruitingINTERVENTIONAL
Enrollment

27

Participants

Timeline

Start Date

August 4, 2021

Primary Completion Date

June 30, 2026

Study Completion Date

February 28, 2030

Conditions
Small Cell Ovarian Carcinoma
Interventions
DRUG

Pembrolizumab 25 MG/ML [Keytruda]

"Pembrolizumab (200mg flat dose) will be administred in combinaison with PAVEP chemotherapy for the first 6 cycles (21-day cycle)~Then, Pembrolizumab (200mg flat dose) will be administred in monotherapy until one year for patients with complete response and up to two years for patients with Stable disease or Progression response after the end of first-sequence therapy (PAVEP chemotherapy +/- High dose chemotherapy) or until disease progression."

Trial Locations (12)

21079

ACTIVE_NOT_RECRUITING

Centre Georges François Leclerc, Dijon

25030

ACTIVE_NOT_RECRUITING

Centre Hospitalier Régional Universitaire de Besançon, Besançon

31059

RECRUITING

Oncopole Claudius Regaud - IUCT Oncopole, Toulouse

33076

ACTIVE_NOT_RECRUITING

Institut Bergonié, Bordeaux

34298

WITHDRAWN

ICM Val d'Aurelle, Montpellier

49055

RECRUITING

ICO - Paul Papin, Angers

49933

ACTIVE_NOT_RECRUITING

Centre Hospitalier Universitaire d'Angers, Angers

59020

ACTIVE_NOT_RECRUITING

Centre Oscar Lambret, Lille

67033

RECRUITING

ICANS - Institut de cancérologie Strasbourg Europe, Strasbourg

69373

RECRUITING

Centre Léon Bérard, Lyon

87042

RECRUITING

CHU de Limoges - Hôpital Dupuytren, Limoges

94805

RECRUITING

Gustave Roussy, Villejuif

All Listed Sponsors
collaborator

Merck Sharp & Dohme LLC

INDUSTRY

lead

ARCAGY/ GINECO GROUP

OTHER