1,550
Participants
Start Date
May 11, 2021
Primary Completion Date
July 30, 2025
Study Completion Date
September 30, 2025
Treatment group
Standard of Care + Local Vancomycin + Local Tobramycin: Participants in the treatment group will receive a dose of 1000mg of Vancomycin powder AND a dose of 1200mg of Tobramycin powder in their wound bed, which is placed right before wound closure at the final stafe of definitive fracture fixation.
Control group
Standard of Care + Local Vancomycin: Participants in the control group will receive a dose of 1000mg of Vancomycin powder in their wound bed, which is placed right before wound closure at the final stage of definitive fracture fixation.
New York Presbyterian/Hospital for Special Surgery, New York
Jamaica Hospital Medical Center, Queens
Penn State College of Medicine, Hershey
University of Pennsylvania Perelman School of Medicine, Philadelphia
Temple University, Philadelphia
University of Maryland Shock Trauma Center, Baltimore
University of Maryland Shock Trauma/Capitol Regions, Baltimore
Inova Fairfax MEdical Campus, Falls Church
University of Virginia, Charlottesville
Virginia Commonwealth University Medical Center, Richmond
Atrium Health Wake Forest Baptist, Winston-Salem
University of North Carolina at Chapel Hill, Chapel Hill
Carolinas Medical Center/Atrium Health Musculoskeletal Health Institute, Charlotte
Medical University of South Carolina -, Charleston
St Mary's University/Tenent Health, West Palm Beach
University of Alabama Heersink School of Medicine, Birmingham
Vanderbilt University, Nashville
University of Mississippi Medical Center, Jackson
University of Kentucky, Lexington
Ohio State University Wexner Medical Center, Columbus
METROHealth, Cleveland
Indiana University School of Medicine - Methodist Hospital, Indianapolis
Indiana University/Eskenazi Health, Indianapolis
Core Well Health, Grand Rapids
University of Wisconsin, Madison
Hennepin County Medical Center, Minneapolis
Loyola University Chicago, Chicago
LSU Health Sciences, New Orleans
University of Oklahoma College of Medicine, Oklahoma City
Baylor Scott & White Research Institute, Dallas
UTHealth/McGovern Medical School, Houston
UT Health San Antonio, San Antonio
University of Colorado Anschutz Medical Campus, Aurora
University of Utah, Salt Lake City
Keck School of Medicine of USC, Los Angeles
Cedars Sinai, West Hollywood
Stanford University, Redwood City
_University of California, San Francisco, San Francisco
Harvard/Mass General/Brigham Hospitals, Boston
Dartmouth Hitchcock, Lebanon
Rhode Island Hospital/Brown University, Providence
United States Department of Defense
FED
Major Extremity Trauma Research Consortium
OTHER