Study to Evaluate the Safety and Antitumor Activity of CX-2009 Monotherapy and in Combination With CX-072 in Advanced Breast Cancer

PHASE2CompletedINTERVENTIONAL
Enrollment

125

Participants

Timeline

Start Date

December 29, 2020

Primary Completion Date

June 2, 2023

Study Completion Date

June 2, 2023

Conditions
NeoplasmsBreast NeoplasmsBreast Neoplasms, Triple-NegativeBreast CancerBreast Neoplasms, Hormone Receptor Positive/HER2 Negative
Interventions
DRUG

CX-2009

Intravenous administration of the CX-2009 of 6 mg/kg administered every 3 weeks (Q3W)

DRUG

CX-072

Intravenous administration of the CX-072 of 1200 mg administered every 3 weeks (Q3W)

Trial Locations (42)

10461

Montefiore Medical Center, The Bronx

13620

Seoul National University Bundang Hospital, Seongnam-si

15213

UPMC Magee-Womens Hospital, Pittsburgh

21201

University of Maryland, Baltimore

21565

Gachon University Gil Medical Center, Incheon

22031

Virginia Cancer Specialists, Fairfax

28034

Hospital Universitario Ramn y Cajal, Madrid

28050

Hospital Universitario HM Sanchinarro, Madrid

NEXT Oncology, Madrid

29425

MUSC, Charleston

32207

Baptist Medical Center, Jacksonville

33705

FCS - North, St. Petersburg

33901

FCS - South, Fort Myers

34952

Hematology Oncology Assoc of the Treasure Coast, Port Saint Lucie

37203

Tennessee Oncology, Nashville

44195

Cleveland Clinic, Cleveland

46010

Hospital Clinico Universitario de Valencia, Valencia

46202

Indiana University Health Melvin and Bren Simon Cancer Center, Indianapolis

53792

University of Wisconsin, Madison

55407

Allina Health System, Minneapolis

60637

University of Chicago Medical Center, Chicago

68130

Nebraska Cancer Specialists, Omaha

75701

UT Health East Texas HOPE Cancer Center, Tyler

78809

Hematology Oncology Clinic, Baton Rouge

80124

Rocky Mountain Cancer Centers, Lone Tree

84112

Huntsman Cancer Institute Research, Salt Lake City

90017

Los Angeles Hematology Oncology Medical, Los Angeles

90033

USC Norris Cancer Center, Los Angeles

90404

UCLA David Geffen, Santa Monica

92093

Moores Cancer Center, La Jolla

99208

Summit Cancer Centers, Spokane

02114

MGH, Boston

02215

DRCI, Boston

Unknown

Soon Chun Hyang University Cheonan Hospital SCHMC, Cheonan

02841

Korea University Anam Hospital, Seoul

05505

Asan Medical Center, Seoul

06273

Gangnam Severance Hospital, Seoul

06351

Samsung Medical Center, Seoul

08036

Hospital Clinic i Provincial de Barcelona, Barcelona

Vall d'Hebron University Hospital, Barcelona

08908

Institut Catala Oncologia, Barcelona

08208

Hospital Parc Tauli, Sabadell

Sponsors
All Listed Sponsors
lead

CytomX Therapeutics

INDUSTRY

NCT04596150 - Study to Evaluate the Safety and Antitumor Activity of CX-2009 Monotherapy and in Combination With CX-072 in Advanced Breast Cancer | Biotech Hunter | Biotech Hunter