100
Participants
Start Date
January 1, 2021
Primary Completion Date
September 1, 2026
Study Completion Date
December 1, 2026
Hyperpolarized Xenon-129 MRI of the lungs
Participants will be imaged using MRI using hyperpolarized xenon-129 gas as a contrast gas
Computed Tomography (CT)
Participants will undergo a CT scan of the thoracic cavity
Pulmonary Function Tests (PFT)
Participants will have their lung function evaluated using PFT
Six Minute Walk Test (6MWT)
Participants will perform the six minute walk test as a measure of exercise capacity
Sputum analysis
Participants will provide a sputum sample that will be analysed for eosinophils
Blood analysis
Participants will have their blood drawn and analysed for eosinophil count.
Questionnaires
Participants will complete questionnaires to assess activity related dyspnea, respiratory symptoms and health status impairment and respiratory related quality of life.
Department of Medicine (Respirology), McMaster University, Hamilton
Collaborators (1)
London Health Sciences Centre
OTHER
Western University, Canada
OTHER