Accelerated Radio-Immunotherapy for Lung Cancer

PHASE2CompletedINTERVENTIONAL
Enrollment

8

Participants

Timeline

Start Date

March 30, 2021

Primary Completion Date

April 15, 2023

Study Completion Date

April 15, 2023

Conditions
Non Small Cell Lung Cancer Stage III
Interventions
COMBINATION_PRODUCT

Nivolumab and Intensity Modulated Radiotherapy (IMRT)

"Every included patient will receive the experimental treatment regimen as follows:~* Combination of IMRT 66 Gray (Gy)/24 fractions of 2.75 Gy) and immunotherapy with 3 doses of nivolumab, 240 mg (1th, 3th and 5th week of IMRT) during 5 weeks~* Maintenance treatment by nivolumab 240 mg (Q2W) during 6 months, or until progression and severe toxicity leading to definitive treatment interruption."

Trial Locations (5)

14076

Centre de Lutte Contre le Cancer François Baclesse, Caen

35042

Valérie JOLAINE, Rennes

44805

Institut de Cancérologie de l'Ouest, Saint-Herblain

Unknown

Centre Hospitalier de Brest, Brest

Centre de Lutte contre le Cancer Oscar Lambret, Lille

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

Bristol-Myers Squibb

INDUSTRY

lead

Center Eugene Marquis

OTHER

NCT04577638 - Accelerated Radio-Immunotherapy for Lung Cancer | Biotech Hunter | Biotech Hunter