43
Participants
Start Date
September 27, 2021
Primary Completion Date
May 30, 2022
Study Completion Date
December 22, 2022
GA2
15 volunteers will receive 50 GA2-infected mosquito bites. The GA2 parasite is a new genetically attenuated Plasmodium falciparum parasite, which arrests development in the liver and should not be able to cause malaria in humans.
GA1
10 volunteers will receive 50 GA1-infected mosquito bites. The GA1 parasite is a genetically attenuated Plasmodium falciparum parasite, which arrests development in the liver and is not able to cause malaria in humans.
Placebo
5 volunteers will receive 50 uninfected mosquito bites.
Leiden University Medical Center, Leiden
Leiden University Medical Center
OTHER