Effect of CAFfeine on Cognition in Alzheimer's Disease

PHASE3RecruitingINTERVENTIONAL
Enrollment

248

Participants

Timeline

Start Date

March 1, 2021

Primary Completion Date

November 30, 2026

Study Completion Date

November 30, 2026

Conditions
Alzheimer Disease
Interventions
DRUG

Caffeine

100mg caffeine capsule treatment, beginning after caffeine diet during 6 weeks, titrate in 3 weeks (by 100mg stages) until 400mg aim dose per day in 2 doses during 27 weeks, and finally interrupt according to the same negative titration.

DRUG

Placebo

Placebo capsule treatment, beginning after caffeine diet during 6 weeks, titrate in 3 weeks until 2 doses aim dose per day during 27 weeks, and finally interrupt according to the same negative titration.

Trial Locations (17)

59037

RECRUITING

Hôpital Roger Salengro, Lille

Unknown

NOT_YET_RECRUITING

CHU Amiens, Amiens

NOT_YET_RECRUITING

CH Arras, Arras

NOT_YET_RECRUITING

CH Beauvais, Beauvais

NOT_YET_RECRUITING

CH Béthune, Béthune

NOT_YET_RECRUITING

CHU Caen, Caen

NOT_YET_RECRUITING

CH Calais, Calais

NOT_YET_RECRUITING

CH Dunkerque, Dunkirk

NOT_YET_RECRUITING

CH Le Quesnoy, Le Quesnoy

NOT_YET_RECRUITING

CH Lens, Lens

NOT_YET_RECRUITING

CHU Lille consultation mémoire Les Bâteliers, Lille

NOT_YET_RECRUITING

CH Roubaix, Roubaix

NOT_YET_RECRUITING

CHU Rouen, Rouen

NOT_YET_RECRUITING

CH Saint Quentin, Saint-Quentin

NOT_YET_RECRUITING

CH Seclin, Seclin

NOT_YET_RECRUITING

CH Tourcoing, Tourcoing

NOT_YET_RECRUITING

CH Valenciennes, Valenciennes

All Listed Sponsors
collaborator

Groupement Interrégional de Recherche Clinique et d'Innovation

OTHER

collaborator

Laboratory of excellence DISTALZ

UNKNOWN

collaborator

Région Nord-Pas de Calais, France

OTHER

collaborator

Meo coffee

UNKNOWN

lead

University Hospital, Lille

OTHER