Feasibility Study to Assess a Trans-nasal Intestinal Potential Difference Probe

NAActive, not recruitingINTERVENTIONAL
Enrollment

15

Participants

Timeline

Start Date

November 12, 2020

Primary Completion Date

April 30, 2027

Study Completion Date

April 30, 2028

Conditions
Inflammatory DiseasePermeability; IncreasedCrohn DiseaseInflammatory Bowel DiseasesEnvironmental Enteropathy
Interventions
DEVICE

IPD Probe via TNIT

A total of 10 healthy adult volunteers will be enrolled in this study. All consented participants will be receive the same intervention. A Nasal tube will be inserted through nares until reaching the small intestine. This will be confirmed by m-mode OCT. Once secured, we will start infusing Ionic solution into the intestine so that IPD Probe can measure the potential difference between this and the control reading. The control reading is measured by infusing the same ionic solution subcutaneously on large muscle groups.

Trial Locations (1)

02114

Massachusetts General Hospital, Boston

All Listed Sponsors
lead

Massachusetts General Hospital

OTHER