High-Intensity Exercise to Attenuate Limitations and Train Habits in Older Adults With HIV

NAActive, not recruitingINTERVENTIONAL
Enrollment

118

Participants

Timeline

Start Date

April 2, 2021

Primary Completion Date

January 24, 2025

Study Completion Date

November 24, 2025

Conditions
HivFatigueMobility Limitation
Interventions
BEHAVIORAL

HIIT (intervention)

Following a 5-minute warm-up, high and moderate-intensity exercise bouts will alternate: a five bouts of 4-minute high-intensity exercise (90% VO2peak) will alternate with four 3-minute bouts of moderate-intensity exercise (50% VO2peak) by week 8. This is followed by a 5-minute cool-down. The total exercise time will be 42 minutes. For resistance exercise, the initial goal will be to complete 3 sets of 8-10 repetitions of 3 exercises at low intensity (50% 1-RM) and then progress to moderate intensity (70-80% 1-RM). Exercise intensity will increase every 4 weeks or when participants can complete more than 8 repetitions with proper form at the prescribed weight.

BEHAVIORAL

CME (active control)

Following a 4-minute warm-up, the participant will walk/jog for up to 42 continuous minutes at 60% VO2peak. This is followed by a 4-minute cool-down. The total exercise time is 50 minutes. For resistance exercise, the initial goal will be to complete 3 sets of 8-10 repetitions of 3 exercises at low intensity (50% 1-RM) and then progress to moderate intensity (70-80% 1-RM). Exercise intensity will increase every 4 weeks or when participants can complete more than 8 repetitions with proper form at the prescribed weight.

Trial Locations (2)

80045

University of Colorado - Anschutz Medical Campus, Aurora

98195

University of Washington, Seattle

All Listed Sponsors
collaborator

Case Western Reserve University

OTHER

collaborator

University of Washington

OTHER

lead

University of Colorado, Denver

OTHER