688
Participants
Start Date
September 18, 2020
Primary Completion Date
December 31, 2024
Study Completion Date
December 31, 2024
Nab-paclitaxel+ trastuzumab+ patuzumab
Nab-paclitaxel 125mg/m2 (days 1, 8, 15) + Trastuzumab (initial loading dose of 8 mg/kg, subsequent maintenance dose of 6 mg/kg) + Pertuzumab (initial loading dose of 840mg, subsequent maintenance dose of 420mg), every 21 days constitute a cycle.
Docetaxel+ carboplatin+ trastuzumab + patuzumab
Docetaxel 75 mg/m2(day 1) + Carboplatin (AUC=6) (day 1) + Trastuzumab (initial loading dose of 8 mg/kg, subsequent maintenance dose of 6 mg/kg) + Pertuzumab (initial loading dose of 840mg, subsequent maintenance dose of 420mg), every 21 days constitute a cycle.
RECRUITING
Henan cancer hospital, Zhengzhou
Henan Cancer Hospital
OTHER_GOV