Imatinib Mesylate in Combination With Pembrolizumab in Patients With Melanoma

PHASE1/PHASE2RecruitingINTERVENTIONAL
Enrollment

22

Participants

Timeline

Start Date

September 14, 2020

Primary Completion Date

October 31, 2024

Study Completion Date

October 31, 2025

Conditions
Melanoma
Interventions
DRUG

Pembrolizumab and Imatinib mesylate

"In Phase Ib study:~Level 1: Imatinib mesylate 200mg QD + Pembrolizumab 200mg Q3W, Level 2: Imatinib mesylate 400mg QD + Pembrolizumab 200mg Q3W"

DRUG

Pembrolizumab and Imatinib mesylate

In Phase II study, eligible patients receive the dose determined in phase Ib cohort.

Trial Locations (1)

1608582

RECRUITING

Keio University Hospital, Shinjuku

Sponsors
All Listed Sponsors
collaborator

Merck Sharp & Dohme LLC

INDUSTRY

collaborator

Ohara Pharmaceutical Co., Ltd.

INDUSTRY

lead

Keio University

OTHER

NCT04546074 - Imatinib Mesylate in Combination With Pembrolizumab in Patients With Melanoma | Biotech Hunter | Biotech Hunter