Combination GRA and SGLT-2i Treatment in Type 1 Diabetes

PHASE1/PHASE2CompletedINTERVENTIONAL
Enrollment

12

Participants

Timeline

Start Date

February 22, 2021

Primary Completion Date

February 28, 2022

Study Completion Date

October 31, 2022

Conditions
Type 1 Diabetes
Interventions
DRUG

Dapagliflozin 10 MG [Farxiga]

4-Week, double-blind, once daily oral 10mg dapagliflozin

DRUG

REMD-477

4-Week, double-blind, once weekly subcutaneous injection with 35mg REMD-477 in 1mL solution.

DRUG

Placebo

4-Week, double-blind, once weekly subcutaneous injection with placebo in 1mL solution.

Trial Locations (1)

92037

UC San Diego Altman Clinical & Translational Research Institute, La Jolla

Sponsors
All Listed Sponsors
collaborator

REMD Biotherapeutics, Inc.

INDUSTRY

collaborator

Juvenile Diabetes Research Foundation

OTHER

collaborator

The Leona M. and Harry B. Helmsley Charitable Trust

OTHER

lead

University of California, San Diego

OTHER