A Study to Compare Bempegaldesleukin (BEMPEG: NKTR-214) Combined With Nivolumab and Tyrosine Kinase Inhibitor (TKI) to Nivolumab and TKI Alone in Participants With Previously Untreated Kidney Cancer That is Advanced or Has Spread

PHASE1CompletedINTERVENTIONAL
Enrollment

30

Participants

Timeline

Start Date

September 11, 2020

Primary Completion Date

January 18, 2024

Study Completion Date

January 18, 2024

Conditions
Renal Cell Carcinoma
Interventions
BIOLOGICAL

Nivolumab

Specified dose on specified days

DRUG

Axitinib

Specified dose on specified days

DRUG

Cabozantinib

Specified dose on specified days

Trial Locations (39)

1419

Local Institution - 0026, Buenos Aires

5400

Local Institution - 0024, San Juan

7600

Local Institution - 0025, Mar del Plata

10065

Local Institution - 0009, New York

13273

Local Institution - 0079, Marseille

14080

Local Institution - 0048, Mexico City

30625

Local Institution - 0045, Hanover

37232

Local Institution, Nashville

40202

Local Institution, Louisville

45070

Local Institution - 0050, Zapopan

45147

Local Institution - 0042, Essen

63110

Local Institution - 0001, St Louis

66460

Local Institution - 0049, Monterrey

72762

Local Institution - 0005, Springdale

76000

Local Institution - 0055, Querétaro

81675

Local Institution - 0044, Munich

90419

Local Institution - 0041, Nuremberg

97080

Local Institution - 0046, Würzburg

97213

Local Institution, Portland

98109

Local Institution - 0007, Seattle

115478

Local Institution - 0059, Moscow

121205

Local Institution - 0052, Moscow

121359

Local Institution - 0087, Moscow

197758

Local Institution - 0058, Saint Petersburg

630099

Local Institution - 0051, Novosibirsk

644013

Local Institution - 0085, Omsk

14784400

Local Institution - 0032, Barretos

77030-3721

Local Institution - 0014, Houston

X5800ALB

Local Institution - 0075, Río Cuarto

30130-090

Local Institution - 0030, Belo Horizonte

80730-150

Local Institution - 0035, Curitiba

91350-200

Local Institution - 0028, Porto Alegre

96830-180

Local Institution - 0036, Santa Cruz do Sul

15090-000

Local Institution - 0029, São José do Rio Preto

T6G 1Z2

Local Institution - 0056, Edmonton

V5Z 4E6

Local Institution - 0015, Vancouver

A1B 3V6

Local Institution - 0022, St. John's

M5G 1Z5

Local Institution - 0008, Toronto

07747

Local Institution - 0040, Jena

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

Nektar Therapeutics

INDUSTRY

lead

Bristol-Myers Squibb

INDUSTRY

NCT04540705 - A Study to Compare Bempegaldesleukin (BEMPEG: NKTR-214) Combined With Nivolumab and Tyrosine Kinase Inhibitor (TKI) to Nivolumab and TKI Alone in Participants With Previously Untreated Kidney Cancer That is Advanced or Has Spread | Biotech Hunter | Biotech Hunter