PET Imaging With [18F]F-AraG in Advanced Non-small Cell Lung Cancer (NSCLC)

PHASE1TerminatedINTERVENTIONAL
Enrollment

4

Participants

Timeline

Start Date

February 1, 2021

Primary Completion Date

November 27, 2023

Study Completion Date

November 27, 2023

Conditions
Non-small Cell Lung Cancer (NSCLC)
Interventions
DRUG

[18F]F-AraG Injection

Single dose of 5 mCi+/- \[18F\]F-AraG IV injection followed by the PET/CT scan. A baseline \[18F\]F-AraG PET/CT will be performed at about 0-7 days before patient receives the first dose of PD-1/PD-L1 immunotherapy. A second \[18F\]F-AraG PET-CT will be performed at less than 14 days after the first dose of PD-1/PD-L1 immunotherapy is administered and before the second dose of PD-1/PD-L1 immunotherapy is given.

Trial Locations (1)

21287

Johns Hopkins University, Baltimore

Sponsors
All Listed Sponsors
collaborator

CellSight Technologies, Inc.

INDUSTRY

collaborator

Stand Up To Cancer

OTHER

lead

Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins

OTHER