Brain Activation and Satiety in Children 2

PHASE3Active, not recruitingINTERVENTIONAL
Enrollment

63

Participants

Timeline

Start Date

January 28, 2021

Primary Completion Date

February 21, 2025

Study Completion Date

February 12, 2026

Conditions
Childhood Obesity
Interventions
BEHAVIORAL

Family Based Behavioral Treatment

Children with obesity accompanied by at least one parent or caregiver will attend 24 weekly sessions. Most sessions will be held via video-conference and include 25-30 min. meetings between an interventionist and each child/parent pair to individualize treatment, followed by separate child and parent group meetings lasting 40 - 45 min. A select few sessions will be held in-person between an interventionist and each child/parent pair with no group session. Parents will serve as primary agents of change for their child and for themselves. Training will focus on food and physical activity education, parenting around food and physical activity, and use of behavioral skills (e.g., self-monitoring, environmental control, contingency management). Intervention groups of 8-12 children/families will be initiated every 3-6 mos. in study yrs. 2-3.

DRUG

Exenatide 2 mg [Bydureon]

Weekly injections of active drug.

DRUG

Placebo

Weekly placebo injections

Trial Locations (1)

98105

Seattle Children's Hospital, Seattle

All Listed Sponsors
collaborator

University of Washington

OTHER

lead

Seattle Children's Hospital

OTHER

NCT04520490 - Brain Activation and Satiety in Children 2 | Biotech Hunter | Biotech Hunter