FEnofibRate as a Metabolic INtervention for COVID-19

PHASE2CompletedINTERVENTIONAL
Enrollment

701

Participants

Timeline

Start Date

August 18, 2020

Primary Completion Date

March 30, 2022

Study Completion Date

March 30, 2022

Conditions
Covid19
Interventions
OTHER

Fenofibrate/fenofibric acid

The randomized intervention will be fenofibrate (Tricor) at a dose of 145 mg/d or dose-equivalent preparation of fenofibrate or fenofibric acid, for 10 days. In all cases, appropriate dose reductions will be implemented for patients with chronic kidney disease as per the approved preparation label. The intended duration of randomized treatment will be for 10 days.

OTHER

Placebo

The control intervention will be a placebo, for 10 days.

OTHER

Usual care

All participants will otherwise receive usual medical care

Trial Locations (1)

19104

University of Pennsylvania Health System, Philadelphia

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

University of Arizona

OTHER

collaborator

Universidad Católica de Santa María

OTHER

collaborator

Hospital Nacional Adolfo Guevara Velasco

OTHER

collaborator

Hospital Nacional Edgardo Rebagliati Martins

OTHER

collaborator

Hospital Nacional Alberto Sabogal Sologuren

OTHER

collaborator

Hospital Nacional Guillermo Almenara Irigoyen

OTHER

collaborator

Hospital Nacional Carlos Alberto Seguin Escobedo - EsSalud

OTHER

collaborator

Universidad de Santander

OTHER

collaborator

National Center for Advancing Translational Sciences (NCATS)

NIH

collaborator

Hospital Civil de Guadalajara

OTHER

collaborator

Hospital Nacional Dos De Mayo

OTHER

collaborator

Hospital Central Fuerza Aérea del Perú

OTHER

collaborator

Hospital Militar Central.Coronel Luis Arias Schereiber

OTHER

collaborator

Hospital Victor Lazarte Echegaray

OTHER

collaborator

University Hospital, Ioannina

OTHER

collaborator

AHEPA University Hospital

OTHER

collaborator

Sotiria Thoracic Diseases Hospital of Athens

OTHER

collaborator

Thriasio General Hospital of Elefsina

OTHER

collaborator

University Hospital, Alexandroupolis

OTHER

collaborator

G.Gennimatas General Hospital

OTHER

collaborator

Biomelab S.A.S.

INDUSTRY

collaborator

Fundación Oftalmológica de Santander. Santander, Colombia

OTHER

collaborator

IPS Centro Científico Asistencial. Barranquilla, Colombia

OTHER

collaborator

Fundación Cardiomet. Quindio, Colombia

OTHER

collaborator

ClÍnica de Marly

OTHER

collaborator

Clínica Internacional

OTHER

lead

University of Pennsylvania

OTHER

NCT04517396 - FEnofibRate as a Metabolic INtervention for COVID-19 | Biotech Hunter | Biotech Hunter