NCT04514029View on ClinicalTrials.gov

Neurotoxicity Prophylaxis With Intrathecal Dexamethasone and Simvastatin Post Axi-Cel

EARLY_PHASE1Active, not recruitingINTERVENTIONAL
Enrollment

37

Participants

Timeline

Start Date

August 6, 2020

Primary Completion Date

November 3, 2023

Study Completion Date

December 31, 2025

Conditions
Lymphoma
Interventions
DRUG

Simvastatin

Simvastatin 40 mg started 2 weeks (+/-5 days) prior to apheresis through day +30

DRUG

Dexamethasone

Intrathecal dexamethasone 8 mg on days -1, +6, +13 (+/-2 days)

Trial Locations (1)

55455

Masonic Cancer Center, University of Minnesota, Minneapolis

All Listed Sponsors
lead

Masonic Cancer Center, University of Minnesota

OTHER