Crystalloid FLUID Choices for Resuscitation of Hospitalized Patients

PHASE4CompletedINTERVENTIONAL
Enrollment

43,626

Participants

Timeline

Start Date

August 15, 2016

Primary Completion Date

June 13, 2020

Study Completion Date

June 13, 2020

Conditions
Fluid Therapy
Interventions
DRUG

Ringer's lactate

Half of the hospitals will be randomized to Ringer's Lactate for a 12 week study period; after a 2 week run-out, the study fluid will be switched to 0.9% saline for another 12 week study period, followed by a 2 week run-out.

DRUG

0.9% saline

Half of the hospitals will be randomized to 0.9% saline for a 12 week study period; after a 2 week run-out, the study fluid will be switched to Ringer's Lactate for another 12 week study period, followed by a 2 week run-out.

Trial Locations (7)

L8L 2X2

Hamilton General Hospital, Hamilton

N6A 5A5

University Hospital, London

N6A 5W9

Victoria Hospital, London

K1K 0T2

Montfort Hospital, Ottawa

K1V7C6

The Ottawa Hospital General Campus, Ottawa

K1Y 4E9

The Ottawa Hospital Civic Campus, Ottawa

K2H 8P4

Queensway Carleton Hospital, Ottawa

All Listed Sponsors
lead

Ottawa Hospital Research Institute

OTHER