Infusion Duration Study To Assess Tolerability of Pegloticase Administered With a Shorter Infusion Duration in Subjects With Uncontrolled Gout Receiving Methotrexate

PHASE4CompletedINTERVENTIONAL
Enrollment

191

Participants

Timeline

Start Date

October 2, 2020

Primary Completion Date

January 18, 2024

Study Completion Date

March 25, 2024

Conditions
Chronic Uncontrolled GoutGoutUncontrolled Gout
Interventions
BIOLOGICAL

Pegloticase with MTX

Participants will receive MTX during the run-in period then pegloticase with MTX for up to 24 weeks during the treatment period

Trial Locations (39)

11702

Long Island Arthritis & Osteoporosis Care, Babylon

16635

Altoona Center for Clinical Research, Duncansville

20745

MD Medical Research, Oxon Hill

28037

Research Carolina Elite, Denver

28144

PMG Research of Salisbury, LLC, Salisbury

28150

Shelby Clinical Research, LLC, Shelby

28451

Cape Fear Arthritis Care, Leland

28602

PMG Research of Hickory, LLC, Hickory

33063

LIFE Clinical Trials, Margate

33064

Napa Research Center, Pompano Beach

GCP Clinical Research, Tampa

33155

D&H National Research Centers, Miami

33166

Prohealth Research Center, Doral

33321

D&H Tamarac Research Centers, Tamarac

33324

IRIS Research and Development, LLC, Plantation

33609

ClinPro Research Solutions, Tampa

33613

ForCare Clinical Research, Tampa

34205

Bradenton Research Center, Bradenton

35294

University of Alabama at Birmingham, Birmingham

37404

Chattanooga Research & Medicine PLLC (CHARM), Chattanooga

45242

Velocity Clinical Research Cincinnati, Cincinnati

70006

MedPharmics, LLC, Metairie

77024

Abigail Rebecca Neiman, MD, PA, Houston

77099

Pioneer Research Solutions Inc - Houston, Houston

80045

University of Colorado Division of Rheumatology, Aurora

80230

Denver Arthritis Clinic, Denver

84088

Velocity Clinical Research, Salt Lake City, West Jordan

85037

Arizona Arthritis & Rheumatology Research, Phoenix

85210

Arthritis & Rheumatology Research, Mesa

85297

Arizona Arthritis & Rheumatology Research, Gilbert

87505

Santa Fe Rheumatology, Santa Fe

90404

Providence Saint John's Health Center, Santa Monica

91042

Medvin Clinical Research, Tujunga

91324

Amicis Research Center, Northridge

91360

Medvin Clinical Research, Thousand Oaks

91722

Medvin Clinical Research, Covina

98021

Western Washington Medical Group, Bothell

99204

Arthritis Northwest, Spokane

99508

Orthopedic Physicians Alaska, Anchorage

Sponsors

Lead Sponsor

All Listed Sponsors
lead

Amgen

INDUSTRY