Niraparib for the Neoadjuvant Treatment of Unresectable Ovarian Cancer

PHASE2Active, not recruitingINTERVENTIONAL
Enrollment

67

Participants

Timeline

Start Date

January 8, 2021

Primary Completion Date

September 25, 2023

Study Completion Date

December 31, 2026

Conditions
Ovarian Cancer
Interventions
DRUG

Niraparib

Neoadjuvant niraparib monotherapy with an individualized starting dose of 200mg/day or 300mg/day based on body weight or platelet count. The 28-day treatment cycle consists of 21 days of medication followed by a 7-day break. Two cycles of neoadjuvant niraparib monotherapy were used, and the investigator may choose to have an additional cycle based on the patient's condition.

Trial Locations (1)

430000

Tongji Hospital, Wuhan

All Listed Sponsors
collaborator

West China Second University Hospital

OTHER

collaborator

Qilu Hospital of Shandong University

OTHER

collaborator

Renmin Hospital of Wuhan University

OTHER

collaborator

Sun Yat-sen University Cancer Center, Sun Yat-sen University

UNKNOWN

collaborator

Guangdong Provincial People's Hospital Affiliated to Southern Medical University

UNKNOWN

lead

Tongji Hospital

OTHER