NCT04506567View on ClinicalTrials.gov

Fractionated and Multiple Dose 225Ac-J591 for Progressive mCRPC

PHASE1/PHASE2Active, not recruitingINTERVENTIONAL
Enrollment

60

Participants

Timeline

Start Date

August 18, 2020

Primary Completion Date

June 1, 2025

Study Completion Date

June 30, 2026

Conditions
Prostate Cancer
Interventions
DRUG

225Ac-J591

Single cycle of fractionated dose of 225Ac-J591

DIAGNOSTIC_TEST

68Ga-PSMA-HBED-CC injection

68Ga-PSMA-HBED-CC PET/CT before and after treatment

DRUG

225Ac-J591

Single dose of 225Ac-J591 every 6 weeks x 4

Trial Locations (2)

10065

Weill Cornell Medicine, New York

11215

Brooklyn Methodist Hospital - New York Presbyterian, Brooklyn

All Listed Sponsors
lead

Weill Medical College of Cornell University

OTHER