Feasibility Study to Evaluate Outpatient Blinatumomab in Subjects With Minimal Residual Disease (MRD) of B-precursor Acute Lymphoblastic Leukemia (ALL)

PHASE4TerminatedINTERVENTIONAL
Enrollment

10

Participants

Timeline

Start Date

August 26, 2021

Primary Completion Date

July 4, 2024

Study Completion Date

September 16, 2024

Conditions
B-precursor Acute Lymphoblastic Leukemia
Interventions
DRUG

Blinatumomab

Participants will receive blinatumomab continuous IV infusion for a maximum of 4 cycles. Each cycle is 6 weeks in duration consisting of 4 weeks of treatment and 2 weeks of rest.

DEVICE

Current Wearable Heatlth Monitoring System (CWHMS)

The study will use the CWHMS device to monitor participants' vital signs while they are at home.

Trial Locations (12)

10029

Mount Sinai Hospital, New York

14642

University of Rochester Cancer Center, Rochester

22908

University of Virginia Health System, Charlottesville

27157

Wake Forest University Health Sciences, Winston-Salem

29607

Saint Francis Hospital, Inc, Greenville

32224

Mayo Clinic, Jacksonville

32804

Adventist Health System/Sunbelt, Inc d/b/a AdventHealth Orlando, Orlando

60068

Advocate Lutheran General Hospital, Park Ridge

68198

University of Nebraska Medical Center, Omaha

90095

University of California Los Angeles, Los Angeles

91010

City of Hope National Medical Center, Duarte

92868-3201

University of California Irvine, Orange

Sponsors

Lead Sponsor

All Listed Sponsors
lead

Amgen

INDUSTRY