96
Participants
Start Date
November 16, 2020
Primary Completion Date
February 28, 2029
Study Completion Date
February 28, 2029
AGN-193408 SR
An implant containing preservative-free AGN-193408 dispersed in a biodegradable polymer matrix. Implants are preloaded into an applicator to facilitate insertion of the implant into the anterior chamber of the study eye.
Lumigan
Control Treatment in Fellow Eye Lumigan 0.01% is a topical eye drop that is a solution containing 0.1 mg/mL bimatoprost
Sham Administration
Needleless applicator contacting similar intracameral insertion location on eye as AGN-193408 SR.
Lumigan Vehicle
Vehicle eye drops (for masking) will be administered once daily in the evening starting on Day 1 in the study eye during Cohort 2.
AGN-193408 SR
An implant containing preservative-free AGN-193408 dispersed in a biodegradable polymer matrix. Implants are preloaded into an applicator to facilitate insertion of the implant in the study eye.
Sham Administration
Needleless applicator contacting similar insertion location on eye as AGN-193408 SR.
Lumigan Vehicle
Vehicle eye drops (for masking) will be administered once daily in the evening starting on Day 1 in the study eye during Cohort 3.
COMPLETED
Scott and Christie and Associates /ID# 252284, Cranberry Township
COMPLETED
Vistar Eye Center /ID# 234811, Roanoke
RECRUITING
Piedmont Eye Center /ID# 246455, Lynchburg
RECRUITING
Private Practice - Dr. James D. Branch /ID# 234560, Winston-Salem
COMPLETED
Asheville Eye Associates /ID# 234963, Asheville
RECRUITING
Coastal Research Associates /ID# 234649, Roswell
RECRUITING
Thomas Eye Group PC /ID# 266775, Sandy Springs
RECRUITING
Logan Ophthalmic Research Inc. /ID# 252087, Tamarac
RECRUITING
Nature Coast Clinical Research - Crystal River /ID# 237781, Crystal River
RECRUITING
East Florida Eye Institute /ID# 235762, Stuart
RECRUITING
Advancing Vision Research /ID# 236683, Smyrna
RECRUITING
Eye Specialty Group /ID# 252201, Memphis
RECRUITING
The Ohio State University /ID# 267590, Columbus
COMPLETED
Indiana University - Glick Eye Institute /ID# 235887, Indianapolis
COMPLETED
Midwest Medical Advisors Inc /ID# 235845, Carmel
RECRUITING
Fraser Eye Care Center /ID# 267100, Fraser
RECRUITING
University of Illinois Hospital and Health Sciences System /ID# 253630, Chicago
RECRUITING
Midwest Vision Research Foundation at Pepose Vision Institute /ID# 267094, Chesterfield
COMPLETED
Tekwani Vision Center /ID# 235149, St Louis
RECRUITING
Silverstein Eye Centers /ID# 266767, Kansas City
RECRUITING
Oklahoma Eye Surgeons /ID# 252089, Oklahoma City
RECRUITING
San Antonio Eye Center /ID# 272087, San Antonio
RECRUITING
Macro Trials (SMO/Network/Consortium) /ID# 266772, Austin
COMPLETED
St. George Eye Center /ID# 236200, St. George
RECRUITING
Horizon Eye Specialists & Lasik Center - Sun City /ID# 252153, Sun City
COMPLETED
United Medical Research Institute /ID# 241701, Inglewood
COMPLETED
Premiere Practice Management LLC /ID# 235957, Torrance
RECRUITING
Wolstan & Goldberg Eye Associates /ID# 241700, Torrance
RECRUITING
Lakeside Vision Center /ID# 241698, Irvine
RECRUITING
Sacramento Eye Consultants /ID# 241697, Sacramento
COMPLETED
Drs Fine Hoffman & Sims LLC /ID# 235919, Eugene
RECRUITING
Global Research Management /ID# 241699, Glendale
RECRUITING
The Eye Research Foundation /ID# 234528, Newport Beach
RECRUITING
Connecticut Eye Consultants P.C. /ID# 235862, Danbury
COMPLETED
University of Florida Health Ophthalmology - Jacksonville /ID# 243122, Jacksonville
RECRUITING
Ophthalmic Consultants of Boston /ID# 236535, Boston
COMPLETED
Rutgers New Jersey Medical School Campus, Doctors Office Center /ID# 234365, Newark
RECRUITING
Northern New Jersey Eye Institute /ID# 241545, South Orange
RECRUITING
Vanderbilt Eye Institute /ID# 266915, Nashville
COMPLETED
Kitasato University Hospital /ID# 238880, Sagamihara-shi
RECRUITING
National Hospital Organization Saitama Hospital /ID# 266953, Wako
COMPLETED
Duplicate_Shimane University Hospital /ID# 238641, Izumo-shi
RECRUITING
The University of Tokyo Hospital /ID# 238871, Bunkyo-ku
RECRUITING
Nippon Medical School Tama Nagayama Hospital /ID# 273428, Tama-shi
RECRUITING
University of Yamanashi Hospital /ID# 238642, Chuo-shi
RECRUITING
Hayashi eye hospital /ID# 267604, Fukuoka
Lead Sponsor
AbbVie
INDUSTRY