Durvalumab and Tremelimumab in Combination With Chemotherapy in HIV-infected Patients With Non-small Cell Lung Cancer

PHASE2RecruitingINTERVENTIONAL
Enrollment

18

Participants

Timeline

Start Date

December 9, 2020

Primary Completion Date

February 28, 2027

Study Completion Date

December 31, 2027

Conditions
Carcinoma, Non-Small Cell Lung
Interventions
DRUG

Durvalumab

durvalumab 1500 mg, intravenous, every 3 weeks for 4 cycles, followed by 1500 mg, intravenous, every 4 weeks (maintenance treatment)

DRUG

Tremelimumab

tremelimumab 75 mg, intravenous, every 3 weeks for 4 cycles. A dose of tremelimumab 75 mg will be given at week 16.

Trial Locations (4)

20007

RECRUITING

Georgetown Lombardi Comprehensive Cancer Center, Washington D.C.

20010

RECRUITING

Medstar Washington Hospital Center, Washington D.C.

21201

RECRUITING

Marlene and Stewart Greenebaum Comprehensive Cancer Center, Baltimore

21237

RECRUITING

Harry and Jeannette Weinberg Cancer Institute at Franklin Square, Baltimore

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

AstraZeneca

INDUSTRY

lead

Georgetown University

OTHER