A Study Evaluating APG-115 as a Single Agent or in Combination With APG-2575 in Subjects With R/R T-PLL and NHL

PHASE2RecruitingINTERVENTIONAL
Enrollment

78

Participants

Timeline

Start Date

July 12, 2021

Primary Completion Date

May 31, 2026

Study Completion Date

May 31, 2027

Conditions
T-Prolymphocytic LeukemiaNon-Hodgkins Lymphoma
Interventions
DRUG

APG-115

QOD, 2 weeks on, 1 week off, in repeated 21-day cycles

DRUG

APG-2575

APG-2575 given orally each day in cycle, in repeated 21-day cycles

Trial Locations (3)

43210

RECRUITING

Ohio State University, Columbus

77030

RECRUITING

MD Anderson, Houston

91010

RECRUITING

City of Hope, Duarte

Sponsors
All Listed Sponsors
lead

Ascentage Pharma Group Inc.

INDUSTRY

NCT04496349 - A Study Evaluating APG-115 as a Single Agent or in Combination With APG-2575 in Subjects With R/R T-PLL and NHL | Biotech Hunter | Biotech Hunter