A Trial to Evaluate Safety, Tolerability, Pharmacokinetics and Preliminary Efficacy of TST001 in Advanced or Metastatic Solid Tumors

PHASE1/PHASE2RecruitingINTERVENTIONAL
Enrollment

320

Participants

Timeline

Start Date

August 13, 2020

Primary Completion Date

February 25, 2025

Study Completion Date

May 1, 2025

Conditions
Advanced Cancer
Interventions
DRUG

TST001

TST001 will be administered by specified doses on specified day

DRUG

Oxaliplatin

Oxaliplatin will be administered by specified doses on specified day

DRUG

Capecitabine

Capecitabine will be administered by specified doses on specified day

DRUG

Paclitaxel

Paclitaxel will be administered by specified doses on specified day

DRUG

Gemcitabine

Gemcitabine will be administered by specified doses on specified day

DRUG

Cisplatin

Cisplatin will be administered by specified doses on specified days Oxaliplatin will be administered by specified doses on specified day Drug: Capecitabine Capecitabine will be administered by specified doses on specified day

DRUG

Nivolumab

Nivolumab will be administered by specified doses on specified day

Trial Locations (40)

100036

RECRUITING

Beijing Cancer Hospital, Beijing

Unknown

RECRUITING

The First Affiliated Hospital of Bengbu Medical College, Bengbu

RECRUITING

Beijing Friendship Hospital, Capital Medical University, Beijing

NOT_YET_RECRUITING

Peking Union Medical College Hospital, Beijing

NOT_YET_RECRUITING

Peking University International Hospital, Beijing

RECRUITING

The First Affiliated Hospital of Chongqing Medical University, Chongqing

RECRUITING

Fujian Cancer Hospital, Fuzhou

RECRUITING

Fujian Medical University Union Hospital, Fuzhou

RECRUITING

The First Affiliated Hospital of Xiamen University, Xiamen

RECRUITING

The Sixth Affiliated Hospital of Sun Yat-sen University, Guangzhou

NOT_YET_RECRUITING

The People's Hospital of Guangxi Zhuang Autonomous Region, Guangxi

RECRUITING

Hainan Provincial People's Hospital, Haikou

RECRUITING

The First Affiliated Hospital of Zhengzhou University, Zhengzhou

RECRUITING

Harbin Medical University Cancer Hospital, Harbin

RECRUITING

Henan Cancer Hospital, Zhengzhou

RECRUITING

Hubei Cancer Hospital, Wuhan

RECRUITING

Zhongnan Hospital of Wuhan University, Wuhan

RECRUITING

Hunan Cancer Hospital, Changsha

RECRUITING

Xiangya Hospital, Central South University, Changsha

RECRUITING

Suzhou Municipal Hospital, Suzhou

RECRUITING

The Second Affiliated Hospital of Soochow University, Suzhou

RECRUITING

Xuzhou Central Hospital, Xuzhou

RECRUITING

The Second Affiliated Hospital of Nanchang University, Nanchang

RECRUITING

Jilin Cancer Hospital, Changchun

RECRUITING

The First Hospital of Jilin University, Changchun

RECRUITING

The First Affiliated Hospital of Jinzhou Medical University, Jinzhou

RECRUITING

Liaoning Cancer Hospital & Institute, Shenyang

RECRUITING

The First Hospital of China Medical University, Shenyang

RECRUITING

Jinan Central Hospital, Jinan

RECRUITING

Linyi Cancer Hospital, Linyi

RECRUITING

The Affiliated Hospital of Qingdao University, Qingdao

RECRUITING

Fudan University Shanghai Cance Center, Shanghai

RECRUITING

Zhongshan Hospital Fudan University, Shanghai

RECRUITING

Sichuan Cancer Hospital, Chengdu

RECRUITING

West China Hospital, Sichuan University, Chengdu

RECRUITING

Tianjin Medical University Cancer Institute & Hospital, Tianjin

RECRUITING

Tianjin Medical University General Hospital, Tianjin

RECRUITING

First Affiliated Hospital of Zhejiang University, Hangzhou

RECRUITING

The Second Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou

RECRUITING

Zhejiang Cancer Hospital, Hangzhou

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

Bristol-Myers Squibb

INDUSTRY

lead

Suzhou Transcenta Therapeutics Co., Ltd.

INDUSTRY

NCT04495296 - A Trial to Evaluate Safety, Tolerability, Pharmacokinetics and Preliminary Efficacy of TST001 in Advanced or Metastatic Solid Tumors | Biotech Hunter | Biotech Hunter