NCT04481919View on ClinicalTrials.gov

Randomized Controlled Trial of urinE chemiStry Guided aCute heArt faiLure treATmEnt (ESCALATE)

PHASE2RecruitingINTERVENTIONAL
Enrollment

474

Participants

Timeline

Start Date

May 1, 2022

Primary Completion Date

September 30, 2026

Study Completion Date

December 31, 2026

Conditions
Heart FailureAcute Heart Failure
Interventions
DRUG

Protocolized diuretic therapy

The urine sodium, urine creatinine and serum creatinine results will be input into the diuretic calculator and the diuretic dose will be chosen based on daily goals for urine output and net negative fluid balance.

Trial Locations (2)

37232

RECRUITING

VA Tennessee Valley Health Service, Nashville

RECRUITING

Vanderbilt University Medical Center, Nashville

All Listed Sponsors
lead

Vanderbilt University Medical Center

OTHER