A Study to Evaluate the Efficacy, Drug Levels and Safety of Luspatercept (ACE-536) for the Treatment of Anemia Due to IPSS-R Very Low, Low, or Intermediate Risk Myelodysplastic Syndromes in Chinese and Japanese Participants With Ring Sideroblasts Who Require Red Blood Cell Transfusions

PHASE2Active, not recruitingINTERVENTIONAL
Enrollment

30

Participants

Timeline

Start Date

November 30, 2020

Primary Completion Date

September 29, 2023

Study Completion Date

February 23, 2026

Conditions
Myelodysplastic Syndromes
Interventions
DRUG

Luspatercept

Specified dose on specified days

Trial Locations (24)

0

Local Institution - 114, Shanghai

100730

Local Institution - 100, Beijing

200233

Local Institution - 101, Shanghai

210029

Local Institution - 108, Nanjing

215006

Local Institution - 104, Suzhu

300020

Local Institution - 106, Tianjin

310006

Local Institution - 102, Hangzhou

325000

Local Institution - 111, Wenzhou

330006

Local Institution - 112, Nanchang

430022

Local Institution - 110, Wuhan

510060

Local Institution - 105, Guangzhou

510080

Local Institution - 103, Guangzhou

510515

Local Institution - 109, Guangzhou

610041

Local Institution - 107, Chengdu, Sichuan

5898511

Local Institution - 210, Sayama

790-8524

Local Institution - 209, Matsuyama

852-8511

Local Institution - 203, Nagasaki

296-8602

Local Institution - 206, Kamogawa

321-0293

Local Institution - 201, Mibu-Machi

545-8585

Local Institution - 205, Osaka

503-8502

Local Institution - 208, Ōgaki

252-0375

Local Institution - 204, Sagamihara

980-8574

Local Institution - 207, Sendai

141-8625

Local Institution - 202, Shinagawa-ku, Tokyo

Sponsors

Lead Sponsor

All Listed Sponsors
lead

Celgene

INDUSTRY