Pupillary Response to Incremental Tetanic Stimulations Under Propofol-remifentanil TCI

NACompletedINTERVENTIONAL
Enrollment

18

Participants

Timeline

Start Date

January 31, 2012

Primary Completion Date

November 30, 2012

Study Completion Date

July 31, 2013

Conditions
Pain
Interventions
PROCEDURE

general anesthesia for scheduled gynecological surgery

DRUG

Propofol

continuous infusion, target concentration adjusted to maintain bispectral index between 45 and 55

DRUG

Remifentanil, Ultiva®

continuous infusion, target concentration 1 ng/ml

PROCEDURE

tetanic stimulations

10-20-30-40-50-60 milliamps, 5 seconds, 100 Hertz 2 minutes between stimulations delivered via the standard neuromuscular blocking agents monitor

DEVICE

VideoAlgesiGraph

non invasive infrared camera placed in front of the left eye of the patients during the study period, connected to a laptop. No part of the device touches the eye.

Trial Locations (1)

75012

Departement d'anesthesie Hopital Armand Trousseau, Paris

All Listed Sponsors
lead

Pr Isabelle CONSTANT

OTHER

NCT04465773 - Pupillary Response to Incremental Tetanic Stimulations Under Propofol-remifentanil TCI | Biotech Hunter | Biotech Hunter